Publications

Selected Publications of CHRC Directors and Collaborators

Wu, X, Xue, L, Tata, A, Song, M, Neto, C*, Xiao, H*. Bioactive components of polyphenol-rich and non-polyphenol rich cranberry fruit extracts and their chemopreventive effects on colitis-associated colon cancer. Journal of Agricultural and Food Chemistry (2020) 68(25): 6845-6853. https://dx.doi.org/10.1021/acs.jafc.0c02604

Turbitt, JR, Colson, KL, Milstead, A, Killday, KB, Neto, CC*. Application of ¹H NMR-based metabolomics to the analysis of cranberry (Vaccinium macrocarpon) supplements. Phytochemical Analysis, 31(1): 68-80 (2020). https://doi.org/10.1002/pca.2867

Bystrom, LM, Hsu, H-T, Zong, H, Lara-Martinez, LA, De Leon, JP, Emmanuel, M, Mery, D, Gardenghi, S, Hassane, D, Neto, CC, Cunningham-Rundles, S, Becker, MW, Rivella, S, Guzman, ML. Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells. Blood Advances, 3 (21): 3261-3265 (2019). DOI: 10.1182/bloodadvances.2018026633

Wu, X, Song, M, Cai, X, Neto, C, Tata, A, Han, Y, Wang, Q, Tang, Z, Xiao, H.* Chemopreventive effects of whole cranberry (Vaccinium macrocarpon) on colitis-associated colon tumerogenesis. Molecular Nutrition & Food Research, 62(24):e1800942 (2018). https://doi.org/10.1002/mnfr.201800942

Neto, CC*, Penndorf, KA, Feldman, M, Meron-Sudai, S, Zakay-Rones, Z, Steinberg, D, Fridman, M, Kashman, Y, Ginsburg, I, Ofek, I, Weiss, EI. Characterization of non-dialyzable constituents from cranberry juice that inhibit adhesion, co-aggregation and biofilm formation by oral bacteria. Food & Function, 8: 1955-1965 (2017). DOI: 10.1039/c7fo00109f

Gupta, P, Song, B, Neto, CC, Camesano, TA*. Atomic force microscopy-guided fractionation reveals the influence of cranberry phytochemicals on adhesion of Escherichia coli.  Food & Function, 7: 2655-2666, (2016). DOI: 10.1039/c6fo00109b

Blumberg, JB, Basu, A, Krueger, CG, Lila, MA, Neto, CC, Novotny, JA, Reed, JD, Rodriguez-Mateos, A, Toner, CD. The Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015. Advances in Nutrition, 7: 759S-770S (2016). https://doi.org/10.3945/an.116.012583

MacPhee, J., Stetson, C.R., Elwood, B.W., Patel, K., McCallum, J., Neto, C., Hurta, R. Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix-metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro. Functional Foods in Health and Disease, 4: 474-492 (2014).

Kim, J., McKeown, B., Jahic, H., Patel, K., Catalli, A., Kulka, M., Neto, C., Hurta, R. Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell-Cycle-Associated Proteins. Functional Foods in Health and Disease, 4: 130-146 (2014).

Carpenter, J.L., Caruso, F.L., Tata, A., Vorsa, N., Neto, C.C. Variation in proanthocyanidin content and composition among commonly grown North American cranberry cultivars (Vaccinium macrocarpon). J. Sci. Food Agric., 94(13): 2738-45 (2014).

Macedo, N.J., Neto, C.C., Liberty, A.M., Ferreira, T.L. Zebrafish as an in vivo Screen for Early Black Cranberry Proanthocyanidin Biomolecular Activity. Am J Mol Biol, 4: 37-48 (2014).

Dao, C.A., Patel, K.D., Neto, C.C. Phytochemicals from the Fruit and Foliage of Cranberry (Vaccinium macrocarpon) - Potential Benefits for Human Health. In Emerging Trends in Dietary Components for Preventing and Combating Disease. Symposium Series, ACS Books, B. Patil, ed; (2013).  

Déziel, B.A.; MacPhee, J.; Patel, K.D.; Catalli, A.; Kulka, M.; Neto, C.C.; Gottschall-Pass, K.T.; Hurta, R.A.R.  American Cranberry (Vaccinium macrocarpon) Extract Affects Human Prostate Cancer Cell Growth Via Cell Cycle Arrest By Modulating Expression of Cell Cycle Regulators. Food and Function, 3: 556-564 (2012).

Patel, KD, Scarano, FJ, Kondo, M, Hurta, RAR, Neto, CC. Proanthocyanidin-rich extracts from cranberry fruit (Vaccinium macrocarpon, Ait.) selectively inhibit the growth of human pathogenic fungi Candida spp. and Cryptococcus neoformans. J. Agric. Food Chem. 59 (24): 12864-12873 (2011).

Su, G, Wei, Y, Guo, M. Direct Colorimetric Detection of Hydrogen Peroxide Using 4-Nitrophenyl Boronic Acid or Its Pinacol Ester, Am. J. Anal. Chem., in press.

Neto, CC. Perspective: Cranberries - Ripe for More Research? J. Sci. Food Agric., 91: 2303–2307 (2011). 

Lu, L, Yue, J, Yuan, C, Zhu, M, Han, H, Liu Z, Guo, M. Ternary oxovanadium(IV) complexes with amino acid-Schiff base and polypyridyl derivatives: Synthesis, characterization, and protein tyrosine phosphatase 1B inhibition, J. Inorg. Biochem. 105: 1323–1328 (2011).

Kondo, M, MacKinnon, SL, Craft, CC, Matchett, MD, Hurta, RAR, and Neto, CC. Ursolic acid and its esters: Occurrence in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells. J. Sci. Food Agric., 91:789-796 (2011).  

MacLean, MA, Scott, BE, Deziel, BA, Liberty, AM, Nunnelley, M, Gottschall-Pass, KT, Neto, CC, Hurta, RAR. North American cranberry (Vaccinium macrocarpon) stimulates apoptotic pathways in DU145 human prostate cancer cells in vitro. Nutr. Cancer, 63: 109-120 (2011).  

Perez, C, Guo, M. Brain-iron dyshomeostasis and Parkinson’s disease. In Metals and Neurodegeneration, Res. Signpost. Huang, S. ed. (2011).

Wei, Y, Zhang, Y, Liu, Z, Guo, M. A novel profluorescent probe for detecting oxidative stress induced by metal and H2O2 in living cells. Chem. Commun. 46: 4472-4774 (2010).

Neto, CC, Dao, CA, Salvas, MR, Autio, WR, Vanden Heuvel, JE., Variation in concentration of phenolic acid derivatives and quercetin glycosides in foliage of cranberry (Vaccinium macrocarpon Ait.) that may play a role in pest deterrence. J. Am. Soc. Hort. Sci., 135: 1-7 (2010). 

Lu, L, Wang, S, Zhu, M, Liu, Z, Guo, M, Xing, S, Fu, X. Inhibition of protein tyrosine phosphatases by an oxovanadium glutamate complex, Na₂[VO(Glu)₂(CH₃OH)],Biometals, 23:1139–1147 (2010).

Wang, Q, Lu, L, Yuan, C, Pei, K, Liu, Z, Guo M, Zhu, M.Potent inhibition of protein tyrosine phosphatase 1B by copper complexes: implication to copper toxicity in biological systems. Chem. Commun., 46: 3547-3549 (2010). 

Déziel, B, Patel, K, Neto, C, Gottschall-Pass, K, Hurta, R. Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Inhibit MMP-2 and MMP-9 Activity in Human Prostate Cancer Cells via Alterations in Multiple Cellular Signalling Pathways. J. Cell. Biochem.,111: 742-54 (2010).  

Yuan, C, Lu, L, Wu, Y, Liu, Z, Guo, M, Xing, S, Fu, X, Zhu, M. Synthesis, characterization, and protein tyrosine phosphatases inhibition activities of oxovanadium(IV) complexes with Schiff base and polypyridyl derivatives, J. Inorg. Biochem. 104, 978-986 (2010).

Wei, Y and Guo, M. A novel H₂O₂-triggered anti-Fenton fluorescent pro-chelator excitable with visible light. Chem. Commun., 45: 1413-1415 (2009). 

Liberty, AM, Amoroso, JW, Hart, PE, Neto, CC, Cranberry PACs and triterpenoids: anti-cancer activities in colon tumor cell lines. Acta Hort., 841: 61-66 (2009).  

Perez, CA, Wei, Y, Guo, M. Iron-binding and anti-Fenton properties of baicalein and baicalin, J. Inorg. Biochem.103: 326-332 (2009).

Tong, Y and Guo, M. Bacterial heme-transport proteins and their heme-coordination modes. Arch. Biochem. Biophys. 483: 1-15 (2009).  

Perez, CA, Tong, Y, Guo, M. Iron Chelators as Potential Therapeutic Agents for Parkinson’s Disease. Curr. Bioactive Comp. 4: 150-158 (2008).

Neto, CC. Cranberry and its Phytochemicals: A Review of in vitro Anticancer Studies. J. Nutr., 137: 186S-193S (2007).  

Guo, M, Perez, C, Wei, Y, Rapoza, E, Su, G, Bou-Abdallah, F, Chasteen, ND. Iron-binding properties of plant phenolics and cranberry’s bio-effects, Dalton Trans. 43: 4951-4961 (2007).

Neto, CC. Cranberry and Blueberry: Evidence for Protective Effects Against Cancer and Vascular Diseases. Mol. Nutr. Food. Res., 51: 652-664 (2007).  

Wei, Y and Guo, M. Hydrogen peroxide triggered prochelator activation, subsequent metal chelation, and attenuation of the Fenton reaction. Angew. Chem. Int. Ed., 46: 4722-4725 (2007).

Neto, CC, Krueger, CG, Lamoureaux, TL, Kondo, M, Vaisberg, AJ, Hurta, RA, Curtis, S, Matchett, MD, Yeung, H, Sweeney-Nixon, MI, Reed, JD. MALDI-TOF MS Characterization of Proanthocyanidins from Cranberry Fruit (Vaccinium macrocarpon) that Inhibit Tumor Cell Growth and Matrix Metalloproteinase Expression in vitro. J. Sci. Food Agric., 86: 18-25 (2006).

Onayemi, OO, Neto, CC, Vanden Heuvel, JE, The Effect of Partial Defoliation on Vine Carbohydrate Concentration and Flavonoid Production in Cranberries. Hort Science 41: 607-611 (2006).

Neto, CC, Sweeney-Nixon, MI, Lamoureaux, TL, Solomon, F, Kondo, M, MacKinnon, SL. Cranberry phenolics: Effects on oxidative processes, neuron cell death and tumor cell growth. Phenolics in Foods and Natural Health Products, ACS Books, Chi-Tang Ho, ed. (2005).

Murphy, BT, MacKinnon, SL, Yan, X, Hammond, GB, Vaisberg, AJ, Neto, CC. Identification of Triterpene Hydroxycinnamates with in vitro Antitumor Activity from Whole Cranberry Fruit (Vaccinium macrocarpon). J. Agric. Food Chem., 51: 3541-3545 (2003).

Yan, X, Murphy, BT, Hammond, GB, Vinson, JA, Neto, CC. Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon). J. Agric. Food Chem., 50: 5844-5849 (2002).