Recent Publications

Selected Publications 

Wu, X, Xue, L, Tata, A, Song, M, Neto, C*, Xiao, H*. Bioactive components of polyphenol-rich and non-polyphenol rich cranberry fruit extracts and their chemopreventive effects on colitis-associated colon cancer. Journal of Agricultural and Food Chemistry (2020) 68(25): 6845-6853. https://dx.doi.org/10.1021/acs.jafc.0c02604.   

Turbitt, JR, Colson, KL, Milstead, A, Killday, KB, Neto, CC*. Application of ¹H NMR-based metabolomics to the analysis of cranberry (Vaccinium macrocarpon) supplements. Phytochemical Analysis, 31(1): 68-80 (2020) https://doi.org/10.1002/pca.2867 

Wu, X, Song, M, Cai, X, Neto, C, Tata, A, Han, Y, Wang, Q, Tang, Z, Xiao, H.* Chemopreventive effects of whole cranberry (Vaccinium macrocarpon) on colitis-associated colon tumerogenesis. Molecular Nutrition & Food Research, 62(24):e1800942 (2018). https://doi.org/10.1002/mnfr.201800942.

Neto, CC*, Penndorf, KA, Feldman, M, Meron-Sudai, S, Zakay-Rones, Z, Steinberg, D, Fridman, M, Kashman, Y, Ginsburg, I, Ofek, I, Weiss, EI. Characterization of non-dialyzable constituents from cranberry juice that inhibit adhesion, co-aggregation and biofilm formation by oral bacteria. Food & Function, 8: 1955-1965 (2017). DOI: 10.1039/c7fo00109f.

Gupta, P., Song, B., Neto, C., Camesano, TA*. Atomic force microscopy-guided fractionation reveals the influence of cranberry phytochemicals on adhesion of Escherichia coli.  Food & Function, 7: 2655-2666, (2016). DOI: 10.1039/c6fo00109b.  

Blumberg, JB*, Basu, A, Krueger, CG, Lila, MA, Neto, CC, Novotny, JA, Reed, JD, Rodriguez-Mateos, A, Toner, CD. The Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015. Advances in Nutrition, 7: 759S-770S (2016). https://doi.org/10.3945/an.116.012583 

Carpenter, J.L., Caruso, F.L., Tata, A., Vorsa, N., Neto, C.C.* Variation in proanthocyanidin content and composition among commonly grown North American cranberry cultivars (Vaccinium macrocarpon). Journal of the Science of Food and Agriculture, 94(13): 2738-45 (2014). 

MacPhee, J., Stetson, C.R., Elwood, B.W., Patel, K., McCallum, J., Neto, C., Hurta, R.* Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix-metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro. Functional Foods in Health and Disease, 4: 474-492 (2014).

Kim, J., McKeown, B., Jahic, H., Patel, K., Catalli, A., Kulka, M., Neto, C., Hurta, R.* Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell-Cycle-Associated Proteins. Functional Foods in Health and Disease, 4: 130-146 (2014).

Macedo, N.J., Neto, C.C., Liberty, A.M., Ferreira, T.L.* Zebrafish as an in vivo Screen for Early Black Cranberry Proanthocyanidin Biomolecular Activity. American Journal Molecular Biology, 4: 37-48 (2014).

Dao, C.A.; Patel, K.D.; Neto, C.C.* Phytochemicals from the Fruit and Foliage of Cranberry (Vaccinium macrocarpon) - Potential Benefits for Human Health. In Emerging Trends in Dietary Components for Preventing and Combating Disease. Symposium Series, ACS Books, B. Patil, ed; 2013.

Déziel, B.A.; MacPhee, J.; Patel, K.D.; Catalli, A.; Kulka, M.; Neto, C.C.; Gottschall-Pass, K.T.; Hurta, R.A.R.*  American Cranberry (Vaccinium macrocarpon) Extract Affects Human Prostate Cancer Cell Growth Via Cell Cycle Arrest By Modulating Expression of Cell Cycle Regulators. Food and Function, 3: 556-564 (2012).

Patel, K.D.; Scarano, F.J.; Kondo, M.; Hurta, R.A.R.; Neto, C.C.*  Proanthocyanidin-rich extracts from cranberry fruit (Vaccinium macrocarpon, Ait.) selectively inhibit the growth of human pathogenic fungi Candida spp. and Cryptococcus neoformans. J Agric Food Chem, 59 (24): 12864-12873 (2011).

Neto, C. C. Perspective: Cranberries - Ripe for More Research? Journal of the Science of Food and Agriculture, 91: 2303–2307 (2011).

Kondo, M, MacKinnon, SL, Craft, CC, Matchett, MD, Hurta, RAR, and Neto, CC. Ursolic acid and its esters: Occurrence in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells. Journal of the Science of Food and Agriculture, 91(5):789-796 (2011).

Neto, C. C. and Vinson, J. A. "Cranberry", in Herbal Medicine: Biomolecular and Clinical Aspects,(Oxidative Stress & Disease Series), Iris Benzie & Sissi Wachtel-Galor (Editors), CRC Press/Taylor & Francis Group. (2011).

MacLean, M.A.; Scott, B.E.; Deziel, B.A.; Liberty, A.M.; Nunnelley, M.; Gottschall-Pass, K.T.; Neto, C.C.; Hurta, R.A.R. North American cranberry (Vaccinium macrocarpon) stimulates apoptotic pathways in DU145 human prostate cancer cells in vitro. Nutrition and Cancer, 63(1): 109-120 (2011).

Neto, C. C. "Ursolic Acid and Other Pentacyclic Triterpenoids: Anticancer Activities and Occurrence in Berries," in Berries and Cancer Prevention, Gary Stoner & Navindra Seeram (Editors), Springer, (2011).

Neto, C. C, Dao, C. A., Salvas, M. R., Autio, W. R., Vanden Heuvel, J. E., Variation in concentration of phenolic acid derivatives and quercetin glycosides in foliage of cranberry (Vaccinium macrocarpon Ait.) that may play a role in pest deterrence. Journal of the American Society of Horticultural Sciences, 135 (6): 1-7 (2010).

Déziel, B.; Patel, K.; Neto, C.; Gottschall-Pass, K.; Hurta, R. "Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Inhibit Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Activity in Human Prostate Cancer Cells via Alterations in Multiple Cellular Signalling Pathways". Journal of Cellular Biochemistry, J Cell Biochem. 111(3):742-54 (2010).

Liberty, A. M., Amoroso, J. W., Hart. P.E., Neto, C. C., Cranberry PACs and triterpenoids: anti-cancer activities in colon tumor cell lines. Proceedings of the Second International Symposium on Human Health Effects of Fruits and Vegetables. Acta Horticulturae, 841: 61-66 (2009).

Neto, C. C., Amoroso, J.W., Liberty, A.M.  Anticancer activities of cranberry phytochemicals: an update.  Molecular Nutrition and Food Research, 52(S1):18-27; published online (May 2008).

Neto, C. C. Cranberry and Blueberry: Evidence for Protective Effects Against Cancer and Vascular Diseases. Molecular Nutrition and Food Research, 51: 652-664 (2007).

Neto, C. C. Cranberry and its Phytochemicals: A Review of in vitro Anticancer Studies. Journal of Nutrition, 137: 186S-193S (2007).

Neto, C. C.; Krueger, C. G., Lamoureaux, T. L.; Kondo, M.; Vaisberg, A. J.; Hurta, R. A. R.; Curtis, S.; Matchett, M. D., Yeung, H.; Sweeney-Nixon, M. I.; Reed, J. D. MALDI-TOF MS Characterization of Proanthocyanidins from Cranberry Fruit ( Vaccinium macrocarpon ) that Inhibit Tumor Cell Growth and Matrix Metalloproteinase Expression in vitro. Journal of the Science of Food and Agriculture, 86: 18-25 (2006).

Neto, C. C.; Sweeney-Nixon, M. I.; Lamoureaux, T. L.; Solomon, F.; Kondo, M.; MacKinnon, S. L. Cranberry phenolics: Effects on oxidative processes, neuron cell death and tumor cell growth. Chapter 22, Symposium Series No. 909: Phenolic Compounds in Foods and Natural Health Products, ACS Books, Shahidi & Ho, ed., (2005).

Vanden Heuvel, J. E., Robidoux, J. L.; Autio, W. R.; Neto, C. C. Timing of partial defoliation affects carbohydrate concentration of vegetative tissues and concentration of phenolics in berries of potted 'De Chaunac' (Vitis / sp.) grapevines. Can. J. Plant Sci. 85 (3) 703-708 (2005).

Langfield, R. D., Scarano, F. J., Heitzman, M. E., Kondo, M., Hammond, G. B., Neto, C. C. Use of a modified microplate bioassay method to investigate antibacterial activity in the Peruvian medicinal plant Peperomia galioides. Journal of Ethnopharmacology, 94: 279-281 (2004).

Murphy, B. T., MacKinnon, S. L., Yan, X., Hammond, G. B., Vaisberg, A. J., Neto, C. C. Identification of Triterpene Hydroxycinnamates with in vitro Antitumor Activity from Whole Cranberry Fruit ( Vaccinium macrocarpon ). Journal of Agricultural and Food Chemistry, 51: 3541-3545 (2003).

Yan, X., Murphy, B. T., Hammond, G. B., Vinson, J. A., Neto, C. C. Antioxidant activities and antitumor screening of extracts from cranberry fruit ( Vaccinium macrocarpon ). Journal of Agricultural and Food Chemistry, 50: 5844-5849 (2002).

Neto, C. C., Owens, C. W., Langfield, R. D., Comeau, A. B., St. Onge, J., Vaisberg, A. J, Hammond, G. B. Antibacterial activity of some Peruvian medicinal plants from the Callejon de Huaylas. Journal of Ethnopharmacology, 79: 133-138 (2002).